BIOVIA Direct

The BIOVIA Direct data cartridge for use with the Oracle database management system improves R&D efficiency, project team collaboration and IP management by enabling scientists to securely register, search, retrieve, explore and compare novel chemical structures and reactions and macromolecular sequences stored in a single, fully searchable database.

BIOVIA Direct and BIOVIA Pipeline Pilot use the same chemistry engine delivering harmonized results regardless of the workflow – The Same Chemistry Everywhere.

What you can do with BIOVIA Direct

BIOVIA Direct supports the widest range of chemical structure types including: small drug-like structures, to mixtures and formulations, polymers, chemically modified sequences and antibody-drug-conjugates (ADC).

The following are supported:

•     Stereochemistry
  
  • tetrahedral and non-tetrahedral
  • enhanced atropisomer support

•     Biologics

•     Polymers

•     Mixtures and Formulations

•     Variable attachment bonds

•     Markush homology groups

•     Generic structures for resitration and queries

•     Haptic and coordination bond

•     Hydrogen bond

•     Reactions

BIOVIA Direct uses a new, hybrid representation that combines the best features of bioinformatics and cheminformatics notations, improving multidisciplinary collaborative research by enabling scientists to:

•     Register and retrieve structures, reactions and biomolecular sequences including peptides, oligonucleotides and oligosaccharides

•     Search for and view chemical modifications in sequences

•     Develop structure-activity correlations in sequences

BIOVIA Direct is database-tested and offers proven performance with databases containing more than 69 million structures and more than 17 million reactions.