CorNeat Vision innovating with biomimicry to launch a new era in medical technology > Dassault Systèmes

Challenge

Diseases affecting the cornea are a major cause of blindness worldwide. Approximately 2 million new cases of corneal blindness are reported each year. Over 30 million people are legally blind in one or both eyes from corneal injury and disease, while many more suffer from degraded visual acuity. A recent study assessed the shortage of corneas at one available for every 70 needed. Existing solutions rely on donor tissue, which can carry disease and have long healing time, while success rates and visual acuity vary between patients.

Corneat vision's matrix inspired by nature to restore vision and health

Disruptive Innovation

CorNeat Vision is a clinical-stage, biomimetic implants and technology company. Our patented, non-degradable, synthetic, platform material, CorNeat EverMatrix™, is set to displace harvested and processed human and animal tissues, and degradable Extra Cellular Matrices (the protein skeleton of the tissue) used in a variety of surgical procedures across diversified fields of medicine.

The CorNeat EverMatrix™ seamlessly and permanently embeds with live tissue without triggering an inflammatory response. Its durability and flexibility, coupled with its bio-integration capabilities, mark a new era of implants that can:

  • Bio-mechanically integrate with surrounding tissue
  • Permanently reinforce soft tissue and accelerate its healing
  • Act as a membrane for guided soft tissue and bone regeneration
  • Conceal irritating implants
  • Enable sensors to continuously remain in contact with surrounding tissue

The features and benefits of the CorNeat EverMatrix™ were proven histologically and clinically in various pre-clinical and clinical trials, including in humans. Findings demonstrate full fibroblast colonization and abundant collagen deposition with no encapsulation, rendering the CorNeat EverMatrix™ an integral part of the surrounding tissue.

The CorNeat KPro, our flagship product, is a novel, self-integrating artificial cornea solution that enables corneally blind patients to regain their full vision potential without relying on donor tissue. The implant leverages a synthetic biomimetic skirt (created from the CorNeat EverMatrix™) and a relatively simple surgical procedure, integrating artificial optics permanently and bio-mechanically within resident ocular tissue. Once available, this will offer global markets a scalable artificial solution for corneal blindness, while eliminating the dependency on donor tissue.

SDG 3-10

Impact

CorNeat Vision supports the UN Sustainable Development Goals by advancing global health and equality through innovative, biomimetic medical solutions that are designed to be widely accessible. By focusing on continuous innovation, growth, and strategic partnerships, the company develops breakthrough technologies that address and permanently resolve complex medical and surgical challenges across multiple therapeutic fields, contributing to Goal 3: Good Health and Well-Being.

At the same time, the company is committed to reducing healthcare disparities worldwide, ensuring that access to advanced medical care is treated as a universal right. Through its business development, distribution networks, clinical operations, and training programs, CorNeat Vision extends its solutions to developing and underserved regions, directly supporting Goal 10: Reduced Inequalities.

Corneat Vision's artificial implant to restore vision and health

Leveraging the 3DEXPERIENCE platform

The 3DEXPERIENCE partnership is a great opportunity for us. While they are already using SolidWorks for product and manufacturing design, they can certainly enjoy some help and access to additional tools as their challenge is now to scale their operation and establish a manufacturing facility. This is in parallel to conducting multiple international clinical trials that needs to be managed. The program’s mentoring support can close some skill gaps they have and enable us to prepare the company toward the launch of its products.

Collaborative & Collective Intelligence

Out-of-the-box thinking is their way of life. They believe in revolutionary thinking across their operations and do not adopt existing practices, systems, processes, and solutions without truly challenging them. CorNeat Vision believes in a multi-disciplinary approach to problem-solving and encourage diversified thinking.

CorNeat Vision

CorNeat Vision

CorNeat Vision is a medical technology company developing innovative biomimetic implants to address unmet needs in ophthalmology and beyond. Its accessible, next-generation solutions aim to restore sight, resolve complex surgical challenges, and expand access to advanced care worldwide.

Meet the Team

CorNeat Vision was founded by Dr. Gilad Litvin and Almog Aley-Raz over five years ago. Gilad and Almog are longtime friends and mountain bike riding partners. Gilad is a serial inventor and gifted ophthalmologist who now spends 80% of his time with the company.

As of today, the company’s growing team consists of 15 employees with a multidisciplinary background and extensive experience in the medical device field. The management team consists of five members. Each member has a specific job and responsibility in which they bring a different level of experience and skills to the table. 

Almog Aley-Raz
CEO and VP R&D
Gilad Litvin
Co-Founder, Chairman
Gerry Tal
VP Quality, Regulatory and Clinical Affairs
Gil Lotan
VP Business Development
Sapir Buchris
VP Operations & Corporate Development

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