Senior Staff Systems Architect
Location: This is a hybrid in-office role, NY
Medidata follows a hybrid office policy in which employees who are hired for an in-person position are expected to work on site a certain number of days per week following Company policy.
About our Company:
Medidata is powering smarter treatments and healthier people through digital solutions to support clinical trials. Celebrating over 25 years of ground-breaking technological innovation across more than 38,000 trials and 12 million patients, Medidata offers industry-leading expertise, analytics-powered insights, and one of the largest clinical trial data sets in the industry. More than 1 million registered users across approximately 2,300 customers trust Medidata's seamless, end-to-end platform to improve patient experiences, accelerate clinical breakthroughs, and bring therapies to market faster. A Dassault Systèmes brand (Euronext Paris: FR0014003TT8, DSY.PA), Medidata is headquartered in New York City and has been recognized as a Leader by Everest Group and IDC. Discover more at www.medidata.com. Listen to our latest podcast, from Dreamers to Disruptors, and follow us at @Medidata.
About the Team:
As we expand our Patient Cloud suite of applications, we are seeking an experienced technologist to lead the architectural evolution of our patient-facing mobile and web applications.
As a Senior Staff Systems Architect, you will be the technical cornerstone of our patient and site-facing digital experiences. You will design and govern solutions which span native mobile applications (iOS/Android), responsive web portals, and the robust API layer that connects them to our core clinical data platform.
You will operate at the intersection of complex clinical workflows and consumer-grade user experiences, ensuring our applications are highly performant, accessible, offline-capable, and strictly compliant with global healthcare regulations (HIPAA, GDPR, FDA 21 CFR Part 11). This role will report to Patient Experience Director, Architecture.
Your Mission:
- Architect the Future: Design a scalable, resilient, and unified frontend and mobile architecture that enables seamless patient participation in clinical trials—whether from their own device (BYOD) or a provisioned clinic tablet.
- Bridge the Stack: Establish the API contracts and micro-frontend/backend-for-frontend (BFF) strategies that allow our mobile and web apps to ingest and transmit critical health data securely and instantly.
- Drive Engineering Excellence: Act as a force multiplier. Mentor staff and senior engineers, set technical standards, and lead cross-functional architecture reviews to eliminate technical debt and ensure cohesive integration across our global platform.
- Champion Site Reliability: Drive an SRE culture across product engineering. Build systems that fail gracefully, recover instantly, and guarantee zero data loss, ensuring the platform is as reliable as the medical care it supports.
Key Responsibilities
- Resilient Mobile & Web Client Architecture: Define the architectural roadmap for a unified client infrastructure spanning mobile and web, focusing on robust state management, seamless data flows, and consistent, high-performance rendering across all patient touchpoints.
- API & Integration Strategy: Design scalable, secure, and versioned APIs and event-driven architectures to bridge patient-facing apps with backend clinical data storage and AI engines.
- Observability & Site Reliability (SRE): Architect comprehensive telemetry and performance monitoring across mobile and web to drive a proactive SRE culture. Define SLOs, SLIs, and error budgets backed by distributed tracing and crash reporting. Coach the team on incident response best practices.
- Security & Compliance: Embed "security-by-design" principles to ensure encryption at rest and in transit, robust identity/access management (SSO, OAuth2), and compliance with strict regulatory frameworks (GCP, HIPAA).
- Cross-Functional Leadership: Partner closely with Product Management, UX/UI, Security, and Cloud Infrastructure teams to translate complex business and regulatory requirements into elegant technical solutions.
Qualifications & Skills
- 10+ years of software engineering experience, with at least 4+ years acting at the Staff level overseeing mobile and web domains.
- Mobile Expertise: Deep technical understanding of the mobile ecosystem, including native app development, cross-platform considerations, app store deployment architectures, and mobile security.
- Web & API Mastery: Mastery of RESTful API principles and backend API design (Ruby on Rails, .NET, Node.js, Java, Go). Experience with modern front end web frameworks (React, Vue, or Angular).
- Cloud Infrastructure: Hands-on architectural experience with AWS, GCP, or Azure.
- Systems Thinking: Proven ability to design complex distributed systems with high availability, fault tolerance, and eventual consistency.
- Communication: Exceptional ability to communicate complex technical concepts to both engineering teams and non-technical executive stakeholders.
As with all roles, Medidata sets ranges based on a number of factors including function, level, candidate expertise and experience, and geographic location. Pay ranges for candidates in locations other than New York City, may differ based on the local market data in that region.
The salary range for positions that will be physically based in New York will be $157,500-$200,000.
Base pay is one part of the Total Rewards that Medidata provides to compensate and recognize employees for their work. Most sales positions are eligible for a commission on the terms of applicable plan documents, and many of Medidata's non-sales positions are eligible for annual bonuses. Medidata believes that benefits should connect you to the support you need when it matters most and provides benefits, including medical, dental, life and disability insurance, 401(k) matching, family leave, flexible paid time off; and 10 paid holidays per year.
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Equal Employment Opportunity:
In order to provide equal employment and advancement opportunities to all individuals, employment decisions at Medidata are based on merit, qualifications and abilities. Medidata is committed to a policy of non-discrimination and equal opportunity for all employees and qualified applicants without regard to race, color, religion, gender, sex (including pregnancy, childbirth or medical or common conditions related to pregnancy or childbirth), sexual orientation, gender identity, gender expression, marital status, familial status, national origin, ancestry, age, disability, veteran status, military service, application for military service, genetic information, receipt of free medical care, or any other characteristic protected under applicable law. Medidata will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
We will accept applications on an ongoing basis until we fill the position.
Inclusion statement
Compensation for the role will be commensurate with experience. The total expected compensation range will be between $157500 and $210000, representing the base salary (or annualized salary based on estimated hourly compensation) and target bonus.

MEDIDATA genera le evidenze e le informazioni necessarie per aiutare le aziende farmaceutiche, biotecnologiche, di dispositivi medici e di diagnostica e i ricercatori nelle università ad accelerare il valore, ridurre al minimo i rischi e ottimizzare i risultati.
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